Current FDA Stance on Sildenafil Citrate for Women

As of March 15, 2021, the Food and Drug Administration (FDA) has not given official approval for the use of Viagra (sildenafil citrate) in women. However, doctors can and sometimes do prescribe it for off-label use.

Off-label Use of Sildenafil in Women

While sildenafil citrate is primarily used to treat erectile dysfunction in males, it is sometimes prescribed off-label for women. Certain healthcare providers prescribe it for sexual performance issues beyond erectile dysfunction, despite the lack of FDA approval for this purpose.

The Efficacy of Sildenafil Citrate in Women with Sexual Dysfunction

Studies have suggested limited evidence that Viagra may be beneficial for women with sexual dysfunction. However, the trials conducted have been small and the results are not definitive. Some speculate that the effects of Viagra could result in increased blood flow to the vulva, potentially aiding with sexual responsiveness. Despite this, Viagra does not appear to be a particularly effective treatment for female sexual dysfunction.

Common Side Effects of Sildenafil Citrate in Women

In studies, the most commonly reported adverse events were headache, flushing, nausea, rhinitis, and visual disturbances. These side effects overlap with those seen when sildenafil is taken for erectile dysfunction. Other side effects may include dizziness, stomach upset, and vision changes such as increased sensitivity to light, blurred vision, or trouble distinguishing between blue and green.

The Role of Sildenafil Citrate (Revatio) in Treating Pulmonary Hypertension

The discussion around sildenafil citrate in women isn't just about sexual function. Sildenafil is also available as Revatio, a medication used to treat pulmonary hypertension in both men and women.

Differences in Response to Sildenafil between Men and Women

Sildenafil treats erectile dysfunction in males by increasing blood flow to the penis. It's speculated that this drug might increase sexual pleasure in women through similar means. However, only two drugs have been approved to treat low libido in females in the United States, and Viagra isn't one of them.

Sildenafil's Potential Effect on Female Genital Area Blood Flow and Orgasm

While it may enhance blood flow to the female genitalia, the efficacy of Viagra in enhancing sexual response, such as increased lubrication or aiding orgasm in women, is not yet confirmed.

More research is needed to substantiate these claims.

Safety Concerns and Drug Interactions with Sildenafil Citrate

Sildenafil citrate is generally a very safe drug, but it can cause a drop in blood pressure due to its effect of opening up blood vessels. Women may experience negative side effects if they use this drug without medical advice. Therefore, it's crucial to take it under the supervision of a healthcare provider.

Consultation with a Doctor before Taking Sildenafil Citrate

Before using sildenafil citrate, women should consult with their healthcare provider. The standard dosage for adults up to 65 years of age is 50 milligrams (mg) as a single dose no more than once a day, 1 hour before sexual intercourse. Alternatively, the medicine may be taken 30 minutes to 4 hours before sexual intercourse. The dosage may be adjusted by a doctor if necessary.

FDA-approved Alternatives to Sildenafil for Women

Given the uncertainty surrounding the effectiveness and safety of sildenafil citrate for women, it may be more beneficial to explore other FDA-approved options for treating sexual dysfunction in women. There are currently two approved drugs for treating low libido in females in the United States.